Randomisation

Our Data Management and Statistics teams can provide advice in the methodology for randomisation and unblinding, and set up of the trial randomisation system.

Our services include:

• development of randomisation methodology and specification
• simulation of randomisation method to check balance across stratification factors
• building and testing a randomisation system, electronic, telephone or paper
• maintain the randomisation system and unblinding procedures
• providing automated email alerts (blind or unblind) for each randomisation event
• providing reports, blinded and unblinded, of group allocation

We can provide an online randomisation using the integrated module within our electronic data capture (EDC) system, Dacima™ Software, or independently to our EDC using Sealed Envelope Ltd © for any study design, including cross-over and double blinded Randomised Controlled Trials. Both systems can be accessed 24 hours a day. We also have experience in setting up a paper based randomisation using sealed envelopes for studies where the online randomisation is not feasible.

Methods of randomisation supported by our CTU include, but are not limited to:

• Simple randomisation
• Mixed blocks randomisation
• Stratified randomisation
• Minimisation
   

Please get in touch with us as soon as you have a research idea so as to get the appropriate support.